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  <title>Shijie Xu — Blog</title>
  <subtitle>Bioinformatics, computational chemistry, deep learning, and mathematics.</subtitle>
  <link href="https://xu-shi-jie.github.io/blogs/feed.xml" rel="self"/>
  <link href="https://xu-shi-jie.github.io/blogs/"/>
  <id>https://xu-shi-jie.github.io/blogs/</id>
  <updated>2026-06-30T00:00:00Z</updated>
  <author><name>Shijie Xu</name></author>
  <entry>
    <title>How does a protein catch a metal? Teaching a computer to find the spot — in seconds</title>
    <link href="https://xu-shi-jie.github.io/blogs/2026-06-16-prime.html"/>
    <id>https://xu-shi-jie.github.io/blogs/2026-06-16-prime.html</id>
    <published>2026-06-16T00:00:00Z</published>
    <updated>2026-06-30T00:00:00Z</updated>
    <summary>How PRIME, our deep-learning method, finds protein metal-binding sites by scattering virtual probes — accurate across 14 metal ions, in ~11 seconds each.</summary>
  </entry>
  <entry>
    <title>2026 年高考数学压轴题：函数与集合 D(x₀)</title>
    <link href="https://xu-shi-jie.github.io/blogs/2026-06-08-gaokao-math.html"/>
    <id>https://xu-shi-jie.github.io/blogs/2026-06-08-gaokao-math.html</id>
    <published>2026-06-08T00:00:00Z</published>
    <updated>2026-07-02T00:00:00Z</updated>
    <summary>2026 年高考数学卷最后一题。已知 f(x) 在 R 上有定义、x&lt;0 时 f(x)=2^x，围绕集合 D(x₀) 证明 f(0)≥1 以及 f 在 [0,+∞) 上单调递增。</summary>
  </entry>
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